MULTI-OMICS DRIVEN PARADIGM FOR CONSTRUCTION OF TRADITIONAL CHINESE MEDICINE ZHENG (SYNDROME) DIAGNOSIS AND TREATMENT MODEL, TAKING SHI ZHENG (SYNDROME OF DAMPNESS) AS AN EXAMPLE

Abstract Background Shi Zheng (SZ, Ghee syndrome of dampness) is a major syndrome type in traditional Chinese Medicine (TCM), the ambiguity of its pathomechanism and the lack of blood diagnostic indicators have limited the understanding of the development of SZ.Purpose To explore the pathological mechanism of SZ and establish a symptom-centered dia

The objective: to assess functional disorders in various models of clinical situations in patients with the severe course of tuberculosis.Subjects and methods.Functional disorders were assessed in 154 tuberculosis patients (HIV positive or HIV negative) with a severe course of the disease, distributing them according to clinical situation models.4

Abstract Health-care decision making should consider the best available evidence, often in the form of systematic reviews (SRs).The number of existing SRs and their overlap make their identification and use difficult.Decision makers often rely on de novo SRs Lanyard instead of using existing SRs.We describe two cases of duplicate reviews (minimum v

Strong evidence has been accumulated since the beginning of the COVID-19 pandemic that neutrophils play an important role in the pathophysiology, particularly in those with severe disease courses.While originally considered to be a rather homogeneous cell type, recent attention to neutrophils has uncovered their fascinating transcriptional MANUKA H

Seed masting and production of empty seeds have often been considered independently as different strategies to reduce seed predation by animals.Here, we integrate both phenomena within the whole assemblage of seed predators (both pre and post-dispersal) and in two contrasting microsites (open vs.sheltered) to improve our understanding of the factor